Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.

Characterizing the functional overlap and mutagenic potential of different pathways of chromosomal double-strand break (DSB) repair is important to understand how mutations arise during cancer development and treatment. To this end, we have compared the role of individual factors in three different...

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Bibliographic Details
Main Authors: Nicole Bennardo, Anita Cheng, Nick Huang, Jeremy M Stark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18584027/pdf/?tool=EBI