Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress

Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress

Summary: Zinc finger protein 521 (Zfp521), a quiescent hematopoietic stem cell (HSC)-enriched transcription factor, is involved in the self-renewal and differentiation of fetal liver HSC. However, its role in adult hematopoiesis remains elusive. Here, we found that Zfp521 deletion did not inhibit ad...

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Bibliographic Details
Main Authors: Zhigang Li, Xuemei Fu, Weiru Wu, Zhilong Liu, Zhe Chen, Chengfang Zhou, Yuanyuan Liu, Mei Kuang, Fangfang Sun, Feifei Xiao, Yongxiu Huang, Xiaojun Zhang, Shijun Fan, Xingqin Huang, Guangling Zheng, Jieping Chen, Yu Hou
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Molecular Biology
Cell Biology
Stem Cell Research
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000079

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http://www.sciencedirect.com/science/article/pii/S2589004221000079

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