Optimizing the Profile of [<sup>99m</sup>Tc]Tc–NT(7–13) Tracers in Pancreatic Cancer Models by Means of Protease Inhibitors

Optimizing the Profile of [<sup>99m</sup>Tc]Tc–NT(7–13) Tracers in Pancreatic Cancer Models by Means of Protease Inhibitors

Background: The overexpression of neurotensin subtype 1 receptors (NTS1Rs) in human tumors may be elegantly exploited for directing neurotensin (NT)-based radionuclide carriers specifically to cancer sites for theranostic purposes. We have recently shown that [<sup>99m</sup>Tc]Tc–DT1 ([&...

Full description

Bibliographic Details
Main Authors: Panagiotis Kanellopoulos, Berthold A. Nock, Eric P. Krenning, Theodosia Maina
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
neurotensin subtype 1 receptor
neurotensin
theranostics
pancreatic cancer
[<sup>99m</sup>Tc]Tc radiotracer
neprilysin
Online Access:https://www.mdpi.com/1422-0067/21/21/7926

Internet

https://www.mdpi.com/1422-0067/21/21/7926

Similar Items