Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection.

Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection.

In the asexual stages, Toxoplasma gondii stage converts between acute phase rapidly replicating tachyzoites and chronic phase slowly dividing bradyzoites. Correspondingly, T. gondii differentially expresses two distinct genes and isoforms of the lactate dehydrogenase enzyme, expressing LDH1 exclusiv...

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Bibliographic Details
Main Authors: Abdelbaset E Abdelbaset, Barbara A Fox, Mohamed H Karram, Mahmoud R Abd Ellah, David J Bzik, Makoto Igarashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5360243?pdf=render

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http://europepmc.org/articles/PMC5360243?pdf=render

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