SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.

Dendritic cells (DCs) are highly specific antigen presenting cells, which link innate and adaptive immune responses and participate in protecting hosts from invading pathogens. DCs can be generated in vitro by culturing human monocytes with GM-CSF and IL-4 followed by LPS induced DC maturation. We s...

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Bibliographic Details
Main Authors: Jin Hu, Ola Winqvist, Amilcar Flores-Morales, Ann-Charlotte Wikström, Gunnar Norstedt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2744869?pdf=render