Statistical properties and robustness of biological controller-target networks.

Cells are regulated by networks of controllers having many targets, and targets affected by many controllers, in a "many-to-many" control structure. Here we study several of these bipartite (two-layer) networks. We analyze both naturally occurring biological networks (composed of transcrip...

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Bibliographic Details
Main Authors: Jacob D Feala, Jorge Cortes, Phillip M Duxbury, Andrew D McCulloch, Carlo Piermarocchi, Giovanni Paternostro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250441?pdf=render