Clinical, pathological and dermoscopic phenotype of MITF p.E318K carrier cutaneous melanoma patients

Clinical, pathological and dermoscopic phenotype of MITF p.E318K carrier cutaneous melanoma patients

Abstract Background The p.E318K variant of the Melanocyte Inducing Transcription Factor (MITF) has been implicated in genetic predisposition to melanoma as an intermediate penetrance allele. However, the impact of this variant on clinico-phenotypic, as well as on dermoscopic patterns features of aff...

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Bibliographic Details
Main Authors: Giulia Ciccarese, Bruna Dalmasso, William Bruno, Paola Queirolo, Lorenza Pastorino, Virginia Andreotti, Francesco Spagnolo, Enrica Tanda, Giovanni Ponti, Cesare Massone, Francesco Drago, Aurora Parodi, Giovanni Ghigliotti, Maria Antonietta Pizzichetta, Paola Ghiorzo, Italian Melanoma Intergroup (I.M.I.)
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Melanocyte Inducing Transcription Factor
E318K
Cutaneous melanoma
Renal cell carcinoma
Nevi
Dysplastic nevi
Online Access:https://doi.org/10.1186/s12967-020-02253-8

Internet

https://doi.org/10.1186/s12967-020-02253-8

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