Old drug repurposing for neglected disease: Pyronaridine as a promising candidate for the treatment of Echinococcus granulosus infections

Background: Cystic echinococcosis (CE), a condition caused by the larval stage of the dog tapeworm Echinococcus granulosus sensu stricto, is a globally distributed zoonotic disease. Current treatment options for CE are limited, and an effective and safe anti-echinococcal drug is urgently required. M...

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Main Authors: Jun Li, Weisi Wang, Junmin Yao, Tian Wang, Shizhu Li, Wenjing Qi, Shuai Han, Yuan Ren, Zhisheng Dang, Xiumin Han, Gang Guo, Baoping Guo, Liqin Wang, Liping Duan, Wenbao Zhang
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300864