Estimating virus effective population size and selection without neutral markers.
By combining high-throughput sequencing (HTS) with experimental evolution, we can observe the within-host dynamics of pathogen variants of biomedical or ecological interest. We studied the evolutionary dynamics of five variants of Potato virus Y (PVY) in 15 doubled-haploid lines of pepper. All plant...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-11-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5720836?pdf=render |