A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma

A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma

Radiation-induced glioma (RIG) is a highly aggressive brain cancer arising as a consequence of radiation therapy. We report a case of RIG that arose in the brain stem following treatment for paediatric medulloblastoma, and the development and characterisation of a matched orthotopic patient-derived...

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Bibliographic Details
Main Authors: Jacqueline P. Whitehouse, Meegan Howlett, Hilary Hii, Chelsea Mayoh, Marie Wong, Paulette Barahona, Pamela Ajuyah, Christine L. White, Molly K. Buntine, Jason M. Dyke, Sharon Lee, Santosh Valvi, Jason Stanley, Clara Andradas, Brooke Carline, Mani Kuchibhotla, Paul G. Ekert, Mark J. Cowley, Nicholas G. Gottardo, Raelene Endersby
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
diffuse midline glioma
radiation-induced glioma
diffuse intrinsic pontine glioma
patient-derived xenograft
medulloblastoma
radiation
Online Access:https://www.mdpi.com/2072-6694/12/10/2937

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https://www.mdpi.com/2072-6694/12/10/2937

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