Integrated High Throughput Analysis Identifies GSK3 as a Crucial Determinant of p53-Mediated Apoptosis in Lung Cancer Cells

Integrated High Throughput Analysis Identifies GSK3 as a Crucial Determinant of p53-Mediated Apoptosis in Lung Cancer Cells

Background/Aims: p53 dysfunction is frequently observed in lung cancer. Although restoring the tumour suppressor function of p53 is recently approved as a putative strategy for combating cancers, the lack of understanding of the molecular mechanism underlying p53-mediated lung cancer suppression has...

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Bibliographic Details
Main Authors: Yu Zhang, Chenyang Zhu, Bangyao Sun, Jiawei Lv, Zhonghua Liu, Shengwang Liu, Hai Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
p53
GSK3
Lung cancer
Apoptosis
Online Access:http://www.karger.com/Article/FullText/478873

Internet

http://www.karger.com/Article/FullText/478873

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