Sex differences in gene expression with galactosylceramide treatment in Cln3Δex7/8 mice.

<h4>Background</h4>CLN3 disease is caused by mutations in the CLN3 gene. The purpose of this study is to discern global expression patterns reflecting therapeutic targets in CLN3 disease.<h4>Methods</h4>Differential gene expression in vehicle-exposed mouse brain was determine...

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Bibliographic Details
Main Authors: Joelle Makoukji, Sally El-Sitt, Nadine J Makhoul, Jihane Soueid, Humam Kadara, Rose-Mary Boustany
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0239537