NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME

NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME

Background. Carriership of CYP4F2*3 (rs2108622, Val433Met) allelic variant can affect antiplatelet effect of clopidogrel, thus changing efficacy and safety of its standard dose.Aim. To study the impact of carriership of at least one CYP4F2*3 allele on the risk of resistance to clopidogrel in patient...

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Bibliographic Details
Main Authors: K. B. Mirzaev, O. D. Konova, E. A. Grishina, K. A. Ryzhikova, Zh. A. Sozaeva, D. A. Andreev, M. Y. Gilyarov, D. A. Sychev
Format: Article
Language:English
Published: Stolichnaya Izdatelskaya Kompaniya 2018-03-01
Series:Racionalʹnaâ Farmakoterapiâ v Kardiologii
Subjects:
cyp4f2
acute coronary syndrome
pharmacogenetics
clopidorgel
p2y12-receptor blockers.
Online Access:https://www.rpcardio.com/jour/article/view/1617

Internet

https://www.rpcardio.com/jour/article/view/1617

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