Decreased plasma Aβ in hyperlipidemic APPSL transgenic mice is associated with BBB dysfunction

Decreased plasma Aβ in hyperlipidemic APPSL transgenic mice is associated with BBB dysfunction

Besides the continued focus on Aβ and Tau in Alzheimer’s disease (AD), it is increasingly evident that other pathologic characteristics, such as vascular alterations or inflammation, are associated with AD. Whether these changes are an initial cause for the onset of AD or occur as a result of the di...

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Bibliographic Details
Main Authors: Tina eLöffler, Stefanie eFlunkert, Magdalena eTemmel, Birgit eHutter-Paier
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Neuroscience
Subjects:
Cerebrovascular Disorders
Cholesterol
Alzheimer’s disease
high-fat diet
Blood Brain Barrier (BBB)
APP mice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00232/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00232/full

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