Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice

Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice

Many risk factors related to the development of non-alcoholic fatty liver disease (NAFLD) have been proposed, including the most well-known of diabetes and obesity as well as periodontitis. As periodontal pathogenic bacteria produce endotoxins, periodontal treatment can result in endotoxemia. The ai...

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Bibliographic Details
Main Authors: Naoki Sasaki, Sayaka Katagiri, Rina Komazaki, Kazuki Watanabe, Shogo Maekawa, Takahiko Shiba, Sayuri Udagawa, Yasuo Takeuchi, Anri Ohtsu, Takashi Kohda, Haruka Tohara, Naoyuki Miyasaka, Tomomitsu Hirota, Mayumi Tamari, Yuichi Izumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
Porphyromonas gingivalis
endotoxemia
non-alcoholic fatty liver disease
periodontitis
gut microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02470/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.02470/full

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