Cellulose-specific Type B carbohydrate binding modules: understanding oligomeric and non-crystalline substrate recognition mechanisms

Cellulose-specific Type B carbohydrate binding modules: understanding oligomeric and non-crystalline substrate recognition mechanisms

Abstract Background Effective enzymatic degradation of crystalline polysaccharides requires a synergistic cocktail of hydrolytic enzymes tailored to the wide-ranging degree of substrate crystallinity. To accomplish this type of targeted carbohydrate recognition, nature produces multi-modular enzymes...

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Bibliographic Details
Main Authors: Abhishek A. Kognole, Christina M. Payne
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biotechnology for Biofuels
Subjects:
Amorphous cellulose
β-Sandwich fold
Carbohydrate–aromatic stacking
Free energy perturbation
Multi-modular glycoside hydrolases
Online Access:http://link.springer.com/article/10.1186/s13068-018-1321-7

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http://link.springer.com/article/10.1186/s13068-018-1321-7

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