Studies on the link between HMG-CoA reductase and cholesterol 7 alpha-hydroxylase in rat liver.
Under most experimental conditions, there is a covariation between the rate-limiting enzyme in cholesterol biosynthesis, HMG-CoA reductase, and the rate-limiting enzyme in bile acid biosynthesis, cholesterol 7 alpha-hydroxylase. The most simple explanation for the coupling between the two enzymes is...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1988-02-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520385461 |