Rhizoma drynariae total flavonoids inhibit the inflammatory response and matrix degeneration via MAPK pathway in a rat degenerative cervical intervertebral disc model

Rhizoma drynariae total flavonoids inhibit the inflammatory response and matrix degeneration via MAPK pathway in a rat degenerative cervical intervertebral disc model

Rhizoma drynariae total flavonoids (RDTF) are extracted from Drynaria fortunei J. Sm (D. fortunei), which was a Chinese herb commonly used to treat fractures and bruises. Modern pharmacological studies indicate flavonoids have anti-inflammatory effect in clinical practice. However, its active ingred...

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Bibliographic Details
Main Authors: Kai Zhao, Min Chen, Ting Liu, Panpan Zhang, Sheng Wang, Xiangguo Liu, Qunan Wang, Jie Sheng
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Rhizoma drynariae total flavonoids
Intervertebral disc degeneration
Model
Inflammation
Intracellular matrix metalloproteinases
Mitogen-activated protein kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221002511

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http://www.sciencedirect.com/science/article/pii/S0753332221002511

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