NLGP counterbalances the immunosuppressive effect of tumor-associated mesenchymal stem cells to restore effector T cell functions

NLGP counterbalances the immunosuppressive effect of tumor-associated mesenchymal stem cells to restore effector T cell functions

Abstract Background A dynamic interaction between tumor cells and its surrounding stroma promotes the initiation, progression, metastasis, and chemoresistance of solid tumors. Emerging evidences suggest that targeting the stromal events could improve the efficacies of current therapeutics. Within tu...

Full description

Bibliographic Details
Main Authors: Tithi Ghosh, Partha Nandi, Nilanjan Ganguly, Ipsita Guha, Avishek Bhuniya, Sarbari Ghosh, Anirban Sarkar, Akata Saha, Shayani Dasgupta, Rathindranath Baral, Anamika Bose
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Stem Cell Research & Therapy
Subjects:
Cystathionase
Dendritic cells
IL-10
Mesenchymal stem/stromal cells
Neem leaf glycoprotein
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s13287-019-1349-z

Internet

http://link.springer.com/article/10.1186/s13287-019-1349-z

Similar Items