Postpartum Circulating Cell-Free Insulin DNA Levels Are Higher in Women with Previous Gestational Diabetes Mellitus Who Develop Type 2 Diabetes in Later Life

Background. Women with previous gestational diabetes mellitus (GDM) have evidence of postpartum β-cell dysfunction, which increases their risk of developing type 2 diabetes (T2DM) later in life. Elevated levels of circulating cell-free preproinsulin (INS) DNA correlate with dying β-cells in both mic...

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Bibliographic Details
Main Authors: Martha Lappas, Harry M. Georgiou, Jane C. Willcox, Michael Permezel, Alexis Shub, Cody-Lee Maynard, Mugdha V. Joglekar, Anandwardhan A. Hardikar
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2019/3264184