Glutathione Levels and Susceptibility to Chemically Induced Injury in Two Human Prostate Cancer Cell Lines

Glutathione Levels and Susceptibility to Chemically Induced Injury in Two Human Prostate Cancer Cell Lines

More aggressive prostate cancer cells (PCCs) are often resistant to chemotherapy. Differences exist in redox status and mitochondrial metabolism that may help explain this phenomenon. Two human PCC lines, PC-3 cells (more aggressive) and LNCaP cells (less aggressive), were compared with regard to ce...

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Bibliographic Details
Main Authors: Lawrence H. Lash, David A. Putt, Adam D. Jankovich
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
glutathione
prostate cancer cells
oxidative stress
apoptosis
stress response
mitochondria
Online Access:http://www.mdpi.com/1420-3049/20/6/10399

Internet

http://www.mdpi.com/1420-3049/20/6/10399

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