Chemoresistance caused by the microenvironment of glioblastoma and the corresponding solutions

Glioblastoma multiforme (GBM) is the most common and aggressive primary human brain tumor. Although comprehensive therapies combining radiotherapy and chemotherapy after surgery can prolong survival, the prognosis is still poor with a median survival of only 14.6 months. Chemoresistance is one of th...

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Bibliographic Details
Main Authors: Xin Zhang, Kaikai Ding, Jian Wang, Xingang Li, Peng Zhao
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218338150