BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.

BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.

Prostate cancer is the second leading cause of cancer-related deaths in men. Activation of MAP kinase signaling pathway has been implicated in advanced and androgen-independent prostate cancers, although formal genetic proof has been lacking. In the course of modeling malignant melanoma in a tyrosin...

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Bibliographic Details
Main Authors: Joseph H Jeong, Zhenxiong Wang, Alexander S Guimaraes, Xuesong Ouyang, Jose L Figueiredo, Zhihu Ding, Shan Jiang, Isil Guney, Gyeong Hoon Kang, Eyoung Shin, William C Hahn, Massimo F Loda, Cory Abate-Shen, Ralph Weissleder, Lynda Chin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2597248?pdf=render

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http://europepmc.org/articles/PMC2597248?pdf=render

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