Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway

Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway

Background: Glaucoma is a progressive optic neuropathy characterized by degeneration of neurons due to loss of retinal ganglion cells (RGCs). High intraocular pressure (HIOP), the main risk factor, causes the optic nerve damage. However, the precise mechanism of HIOP-induced RGC death is not yet com...

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Bibliographic Details
Main Authors: Yi Li, Yan-Ming Chen, Ming-Ming Sun, Xiao-Dan Guo, Ya-Chen Wang, Zhong-Zhi Zhang
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Apoptosis; Glaucoma; Hydrostatic Pressure; Laminin; Retinal Ganglion Cells
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=8;spage=976;epage=983;aulast=Li

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=8;spage=976;epage=983;aulast=Li

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