Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients

Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients

Abstract In the “precision oncology” era the characterization of tumor genetic features is a pivotal step in cancer patients’ management. Liquid biopsy approaches, such as analysis of cell-free DNA from plasma, represent a powerful and noninvasive strategy to obtain information about the genomic sta...

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Bibliographic Details
Main Authors: Filippo Martignano, Uday Munagala, Stefania Crucitta, Alessandra Mingrino, Roberto Semeraro, Marzia Del Re, Iacopo Petrini, Alberto Magi, Silvestro G. Conticello
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Cancer
Subjects:
Copy number aberrations. Diagnosis
Metastasis
Plasma
Third generation sequencing
cfDNA
ctDNA
Online Access:https://doi.org/10.1186/s12943-021-01327-5

Internet

https://doi.org/10.1186/s12943-021-01327-5

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