Oxygen Sensing and Viral Replication: Implications for Tropism and Pathogenesis

The ability to detect and respond to varying oxygen tension is an essential prerequisite to life. Several mechanisms regulate the cellular response to oxygen including the prolyl hydroxylase domain (PHD)/factor inhibiting HIF (FIH)-hypoxia inducible factor (HIF) pathway, cysteamine (2-aminoethanethi...

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Bibliographic Details
Main Authors: Peter Jianrui Liu, Peter Balfe, Jane A McKeating, Mirjam Schilling
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
HIF
PHD
2OG
Online Access:https://www.mdpi.com/1999-4915/12/11/1213