Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial.

Although host immune response is an emerging prognostic factor for colorectal cancer, there is no consensus on the optimal methodology, surrogate markers or tissue for study.Tumour blocks were prospectively collected from 344 patients with stage II/III colorectal cancer (CRC) treated with adjuvant c...

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Main Authors: George Pentheroudakis, Georgia Raptou, Vassiliki Kotoula, Ralph M Wirtz, Eleni Vrettou, Vasilios Karavasilis, Georgia Gourgioti, Chryssa Gakou, Konstantinos N Syrigos, Evangelos Bournakis, Grigorios Rallis, Ioannis Varthalitis, Eleni Galani, Georgios Lazaridis, George Papaxoinis, Dimitrios Pectasides, Gerasimos Aravantinos, Thomas Makatsoris, Konstantine T Kalogeras, George Fountzilas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4430485?pdf=render