Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture
Abstract The hematopoietic stem cell (HSC) niche has been extensively studied in bone marrow, yet a more systematic investigation into the microenvironment regulation of hematopoiesis in fetal liver is necessary. Here we investigate the spatial organization and transcriptional profile of individual...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-021-00266-1 |