No-Go Zones for Mariner Transposition
The property of transposons to randomly insert into target DNA has long been exploited for generalized mutagenesis and forward genetic screens. Newer applications that monitor the relative abundance of each transposon insertion in large libraries of mutants can be used to evaluate the roles in cellu...
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-10-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/5/e01690-16 |