No-Go Zones for Mariner Transposition

The property of transposons to randomly insert into target DNA has long been exploited for generalized mutagenesis and forward genetic screens. Newer applications that monitor the relative abundance of each transposon insertion in large libraries of mutants can be used to evaluate the roles in cellu...

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Bibliographic Details
Main Author: Brian J. Akerley
Format: Article
Language:English
Published: American Society for Microbiology 2016-10-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/5/e01690-16