Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellular vesicles.

Bibliographic Details
Main Authors: Eduardo Reátegui, Kristan E. van der Vos, Charles P. Lai, Mahnaz Zeinali, Nadia A. Atai, Berent Aldikacti, Frederick P. Floyd, Aimal H. Khankhel, Vishal Thapar, Fred H. Hochberg, Lecia V. Sequist, Brian V. Nahed, Bob S. Carter, Mehmet Toner, Leonora Balaj, David T. Ting, Xandra O. Breakefield, Shannon L. Stott
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02261-1