PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression

PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression

How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear. Our previous studies suggest that PexRAP, a peroxisomal lipid synthetic enzyme, regulates PPARγ signaling and whi...

Full description

Bibliographic Details
Main Authors: Irfan J. Lodhi, John M. Dean, Anyuan He, Hongsuk Park, Min Tan, Chu Feng, Haowei Song, Fong-Fu Hsu, Clay F. Semenkovich
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
adipose tissue
adipocyte browning
beige fat
obesity
UCP1
PRDM16
PPARγ
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312196

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717312196

Similar Items