PI3K/AKT Signaling Pathway Is Essential for Survival of Induced Pluripotent Stem Cells.

Apoptosis is a highly conserved biochemical mechanism which is tightly controlled in cells. It contributes to maintenance of tissue homeostasis and normally eliminates highly proliferative cells with malignant properties. Induced pluripotent stem cells (iPSCs) have recently been described with signi...

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Bibliographic Details
Main Authors: Amir M Hossini, Annika S Quast, Michael Plötz, Katharina Grauel, Tarik Exner, Judit Küchler, Harald Stachelscheid, Jürgen Eberle, Anja Rabien, Evgenia Makrantonaki, Christos C Zouboulis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4854383?pdf=render