Short Read Alignment Based on Maximal Approximate Match Seeds
Sequence alignment is a critical step in many critical genomic studies, such as variant calling, quantitative transcriptome analysis (RNA-seq), and metagenomic sequence classification. However, the alignment performance is largely affected by repetitive sequences in the reference genome, which exten...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Molecular Biosciences |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2020.572934/full |