Propofol induces mitochondrial-associated protein LRPPRC and protects mitochondria against hypoxia in cardiac cells

Background Hypoxia-induced oxidative stress is one of the main mechanisms of myocardial injury, which frequently results in cardiomyocyte death and precipitates life-threatening heart failure. Propofol (2,6-diisopropylphenol), which is used to sedate patients during surgery, was shown to strongly af...

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Bibliographic Details
Main Authors: Qianlu Zhang, Shiwei Cai, Liping Guo, Guojun Zhao, Partha Mukhopadhyay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478836/?tool=EBI