The Interplay of HIV-1 and Macrophages in Viral Persistence

The Interplay of HIV-1 and Macrophages in Viral Persistence

HIV-1 has evolved mechanisms to evade host cell immune responses and persist for lifelong infection. Latent cellular reservoirs are responsible for this persistence of HIV-1 despite the powerful effects of highly active antiretroviral therapies (HAART) to control circulating viral load. While cellul...

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Bibliographic Details
Main Authors: Chynna M. Hendricks, Thaissa Cordeiro, Ana Paula Gomes, Mario Stevenson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
HIV
reservoirs
macrophages
latency
functional cure
host factors
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.646447/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.646447/full

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