Caspases and matrix metalloproteases facilitate collective behavior of non-neural ectoderm after hindbrain neuropore closure

Caspases and matrix metalloproteases facilitate collective behavior of non-neural ectoderm after hindbrain neuropore closure

Abstract Background Mammalian brain is formed through neural tube closure (NTC), wherein both ridges of opposing neural folds are fused in the midline and remodeled in the roof plate of the neural tube and overlying non-neural ectodermal layer. Apoptosis is widely observed from the beginning of NTC...

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Bibliographic Details
Main Authors: Naomi Shinotsuka, Yoshifumi Yamaguchi, Kenichi Nakazato, Yudai Matsumoto, Atsushi Mochizuki, Masayuki Miura
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Developmental Biology
Subjects:
Apoptosis
Caspases
Matrix metalloproteases
Neural tube closure
Live-imaging
Online Access:http://link.springer.com/article/10.1186/s12861-018-0175-3

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http://link.springer.com/article/10.1186/s12861-018-0175-3

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