Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Summary: Neutrophil granule proteases are thought to function as anti-microbial effectors, cooperatively hydrolyzing microorganisms within phagosomes, or upon deployment into the extracellular space. However, evidence also suggests that neutrophil proteases play an important role in the coordination...

Full description

Bibliographic Details
Main Authors: Danielle M. Clancy, Graeme P. Sullivan, Hannah B.T. Moran, Conor M. Henry, Emer P. Reeves, Noel G. McElvaney, Ed C. Lavelle, Seamus J. Martin
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718302560

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718302560

Similar Items