Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization

We examined the effects of apolipoprotein E (apoE) domain structure and polymorphism on the kinetics of solubilization (clearance) of dimyristoyl-phosphatidylcholine multilamellar vesicles. This second order reaction consisted of two simultaneous kinetic phases; it also exhibited saturable kinetics...

Full description

Bibliographic Details
Main Authors: Mark L. Segall, Padmaja Dhanasekaran, Faye Baldwin, G.M. Anantharamaiah, Karl H. Weisgraber, Michael C. Phillips, Sissel Lund-Katz
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327887