New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells.

New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells.

Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong interferon-stimulated gene (ISG) response in human endothelial cells. African green monkey-derived Vero E6 cells are used to propagate hantaviruses as well a...

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Bibliographic Details
Main Authors: Joseph Prescott, Pamela Hall, Mariana Acuna-Retamar, Chunyan Ye, Marc G Wathelet, Hideki Ebihara, Heinz Feldmann, Brian Hjelle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887373?pdf=render

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http://europepmc.org/articles/PMC2887373?pdf=render

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