Cuprizone and EAE mouse frontal cortex proteomics revealed proteins altered in multiple sclerosis

Abstract Two pathophysiological different experimental models for multiple sclerosis were analyzed in parallel using quantitative proteomics in attempts to discover protein alterations applicable as diagnostic-, prognostic-, or treatment targets in human disease. The cuprizone model reflects de- and...

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Bibliographic Details
Main Authors: Eystein Oveland, Intakhar Ahmad, Ragnhild Reehorst Lereim, Ann Cathrine Kroksveen, Harald Barsnes, Astrid Guldbrandsen, Kjell-Morten Myhr, Lars Bø, Frode S. Berven, Stig Wergeland
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86191-5