TREM2 Acts as a Tumor Suppressor in Colorectal Carcinoma through Wnt1/<i>β</i>-catenin and Erk Signaling

TREM2 (triggering receptor expressed on myeloid cells) is involved in the development of malignancies. However, the function of TREM2 in colorectal cancer has not been clearly elucidated. Here, we investigated TREM2 function for the first time in colorectal epithelial cancer cells and demonstrated t...

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Bibliographic Details
Main Authors: Su-Man Kim, Eun-Mi Kim, Kon-Young Ji, Hwa-Youn Lee, Su-Min Yee, Su-Min Woo, Ja-Woon Yi, Chul-Ho Yun, Harim Choi, Hyung-Sik Kang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
Erk
Online Access:https://www.mdpi.com/2072-6694/11/9/1315