Control of Cell Growth and Proliferation by the Tribbles Pseudokinase: Lessons from Drosophila

The Tribbles (Trib) family of pseudokinase proteins regulate cell growth, proliferation, and differentiation during normal development and in response to environmental stress. Mutations in human Trib isoforms (Trib1, 2, and 3) have been associated with metabolic disease and linked to leukemia and th...

Full description

Bibliographic Details
Main Authors: Leonard L. Dobens, Christopher Nauman, Zachary Fischer, Xiaolan Yao
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/4/883