Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells.

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells.

Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through Proliferator Activator Receptor (PPARα) -dependent d...

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Bibliographic Details
Main Authors: Vishwaroop Mulay, Peta Wood, Melanie Manetsch, Masoud Darabi, Rose Cairns, Monira Hoque, Karen Cecilia Chan, Meritxell Reverter, Anna Alvarez-Guaita, Kerry-Anne Rye, Carles Rentero, Joerg Heeren, Carlos Enrich, Thomas Grewal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3636258?pdf=render

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http://europepmc.org/articles/PMC3636258?pdf=render

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