The Role of Primary Cilia in the Crosstalk between the Ubiquitin–Proteasome System and Autophagy

Protein degradation is a pivotal process for eukaryotic development and homeostasis. The majority of proteins are degraded by the ubiquitin–proteasome system and by autophagy. Recent studies describe a crosstalk between these two main eukaryotic degradation systems which allows for establi...

Full description

Bibliographic Details
Main Authors: Antonia Wiegering, Ulrich Rüther, Christoph Gerhardt
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
IFT
GLI
Online Access:http://www.mdpi.com/2073-4409/8/3/241