MYLK4 promotes tumor progression through the activation of epidermal growth factor receptor signaling in osteosarcoma

MYLK4 promotes tumor progression through the activation of epidermal growth factor receptor signaling in osteosarcoma

Abstract Background Osteosarcoma (OS) is the most common primary bone cancer in adolescents and lung metastasis is the leading cause of death in patients with OS. However, the molecular mechanisms that promote OS growth and metastasis remain unknown. Methods We investigated the expression of myosin...

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Bibliographic Details
Main Authors: Mengkai Yang, Tao Zhang, Yangfeng Zhang, Xiaojun Ma, Jing Han, Ke Zeng, Yafei Jiang, Zongyi Wang, Zhuoying Wang, Jing Xu, Yingqi Hua, Zhengdong Cai, Wei Sun
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MYLK4
Osteosarcoma
Epidermal growth factor receptor
Growth
Metastasis
Online Access:https://doi.org/10.1186/s13046-021-01965-z

Internet

https://doi.org/10.1186/s13046-021-01965-z

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