Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75

Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75

Vascular endothelial growth factor C (VEGF-C) plays a critical role in tumor lymphangiogenesis and lymph node metastasis. We report here that VEGF-C expression is regulated by microenvironmental stress including hyperthermia and oxidative stress. Furthermore, we show that this stress response is me...

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Bibliographic Details
Main Authors: Batya Cohen, Yoseph Addadi, Stav Sapoznik, Gila Meir, Vyacheslav Kalchenko, Alon Harmelin, Shifra Ben-Dor, Michal Neeman
Format: Article
Language:English
Published: Elsevier 2009-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800456

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http://www.sciencedirect.com/science/article/pii/S1476558609800456

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