SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model

SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model

Abstract Background Right ventricular (RV) angiogenesis has been associated with adaptive myocardial remodeling in pulmonary hypertension (PH), though molecular regulators are poorly defined. Endothelial cell VEGFR-2 is considered a “master regulator” of angiogenesis in other models, and the small m...

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Bibliographic Details
Main Authors: Grace L. Peloquin, Laura Johnston, Mahendra Damarla, Rachel L. Damico, Paul M. Hassoun, Todd M. Kolb
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Respiratory Research
Subjects:
Right ventricle
Angiogenesis
Pulmonary hypertension
Cardiac endothelial cell
VEGFR-2
Online Access:http://link.springer.com/article/10.1186/s12931-019-1079-x

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http://link.springer.com/article/10.1186/s12931-019-1079-x

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