Investigating the Effect of Ligand Amount and Injected Therapeutic Activity: A Simulation Study for 177Lu-Labeled PSMA-Targeting Peptides.

Investigating the Effect of Ligand Amount and Injected Therapeutic Activity: A Simulation Study for 177Lu-Labeled PSMA-Targeting Peptides.

In molecular radiotherapy with 177Lu-labeled prostate specific membrane antigen (PSMA) peptides, kidney and/or salivary glands doses limit the activity which can be administered. The aim of this work was to investigate the effect of the ligand amount and injected activity on the tumor-to-normal tiss...

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Bibliographic Details
Main Authors: Peter Kletting, Christiane Schuchardt, Harshad R Kulkarni, Mostafa Shahinfar, Aviral Singh, Gerhard Glatting, Richard P Baum, Ambros J Beer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017739?pdf=render

Internet

http://europepmc.org/articles/PMC5017739?pdf=render

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