Integrated Multi-Omic Analysis of Mycobacterium tuberculosis H37Ra Redefines Virulence Attributes

Integrated Multi-Omic Analysis of Mycobacterium tuberculosis H37Ra Redefines Virulence Attributes

H37Ra is a virulence attenuated strain of Mycobacterium tuberculosis widely employed as a model to investigate virulence mechanisms. Comparative high-throughput studies have earlier correlated its avirulence to the presence of specific mutations or absence of certain proteins. However, a recent sequ...

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Bibliographic Details
Main Authors: Sneha M. Pinto, Renu Verma, Jayshree Advani, Oishi Chatterjee, Arun H. Patil, Saketh Kapoor, Yashwanth Subbannayya, Remya Raja, Sheetal Gandotra, T. S. Keshava Prasad
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
next-generation sequencing
orbitrap
genome annotation
virulence attenuation
multiomics
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01314/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01314/full

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