Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.

Integrin α(D)β(2) is the most recently identified member of the leukocyte, or β(2), subfamily of integrin heterodimers. Its distribution and functions on human leukocytes have not been clearly defined and are controversial. We examined these issues and found that α(D)β(2) is prominently expressed by...

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Bibliographic Details
Main Authors: Yasunari Miyazaki, Adriana Vieira-de-Abreu, Estelle S Harris, Amrapali M Shah, Andrew S Weyrich, Hugo C Castro-Faria-Neto, Guy A Zimmerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4240710?pdf=render